The world-wide spread of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 is the third major coronavirus outbreak in the past 20 years. SARS-CoV-2 is closely related to SARS-CoV, several SARS-....
2021-03-19
MedComm
Metabolic reprogramming with heterogeneity is a hallmark of cancer and is at the basis of malignant behaviors. It supports the proliferation and metastasis of tumor cells according to the low nutritio....
2021-02-27
Mol Biomed
COVID-19 is leading to a global pandemic and invades human cells via ACE2. So ACE2 is considered to be the receptor in host cells for binding to this novel virus. Therefore, the target cells with the ....
2021-02-22
MedComm
Nasopharyngeal carcinoma (NPC) is a squamous carcinoma involving genetic predisposition, infection with Epstein-Barr virus (EBV), and environmental factors, with apparent geographical and racial distr....
2021-02-10
MedComm
Ran (Ras-related nuclear) protein is a member of the Ras superfamily of small GTPases. Like other GTPases, Ran switches between GDP-bound (inactive) and GTP-bound (active) states. Multiple missense mu....
2021-02-07
Mol Biomed
Dysregulated lipid metabolism represents an important metabolic alteration in cancer. Fatty acids, cholesterol, and phospholipid are the three most prevalent lipids that act as energy producers, signa....
2021-01-31
MedComm
IPlatinating agents such as cisplatin and carboplatin are commonly used in the treatment of ovarian cancer. However not all patients respond and the development of intrinsic or acquired resistance to ....
2021-01-28
Mol Biomed
As a group of RTKs family, fibroblast growth factor receptors (FGFRs) play critical roles in many key behaviors, including cell proliferation, migration, differentiation, and survival. As their ligand....
2021-01-18
MedComm
Inflammatory changes caused by viruses, bacteria, exposure to toxins, commonly used drugs and even surgical intervention have the potential of causing abnormal epithelial permeability, which is manife....
2021-01-14
Mol Biomed