MedComm-Future Medicine | Cryoprotectants for red blood cells: Evaluate safety and effectiveness by in vitro measures

History of the development of small molecule- and macromolecule-based cryoprotectants for red blood cell cryopreservation. DMSO, dimethyl sulfoxide.The transfusion of red blood cells (RBCs) is crucial....

2023-12-31

MedComm-Biomaterials and Applications | Development of nanoparticle-based drug delivery system for inflammation treatment and diagnosis

Schematic diagram of nanoparticles, cells carrying nanoparticles, and nanoparticles encapsulated by cell membranes in the site of vascular inflammation. The lower part of the figure is classification ....

2023-12-31

MedComm-Oncology | Cancer stem cells: Signaling pathways and therapeutic targeting

This figure explains the origin of cancer stem cells (CSCs) and the cause of conventional antitumor therapy failure due to the survival capability of these CSCs under the extreme conditions created du....

2023-12-31

MedComm-Future Medicine | Awareness of high and pathological myopia among myopic patients in China: A cross-sectional multicenter survey

Flowchart depicting the screening process for the study participants.This study aimed to investigate the awareness of high and pathological myopia among patients with high myopia. A cross-sectional mu....

2023-11-30

MedComm-Biomaterials and Applications | Advances in organ-on-a-chip for the treatment of cardiovascular diseases

This figure compares OoC with 2D cell culture, organoids, and animal models and outlines the advantages and disadvantages. Figures were created with Photoshop CS6.Cardiovascular disease (CVD) is curre....

2023-11-30

MedComm-Oncology | COVID-19 and cancer: Dichotomy of the menacing dilemma

Characteristics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The diagram summarizes the taxonomy, symptoms, pathophysiology, and variants of the SARS-CoV-2 virus.The coronavirus di....

2023-11-30

MedComm-Future Medicine | Oncolytic viral therapy as promising immunotherapy against glioma

Antitumor effects of oncolytic virus (OVs) in brain tumor. (1) OVs can selectively infect tumor cells and induce tumor cells lysis including apoptosis, pyroptosis, and necroptosis. (2) Innate immune r....

2023-10-31

MedComm-Biomaterials and Applications | Exploring the potential of transethosomes in therapeutic delivery: A comprehensive review

Schematic illustration of various lipid-based nanocarriers with phospholipid, ethanol, and surfactant (liposome, transethosome, transferosome, and ethosome).The growing need for innovative drug delive....

2023-10-31

MedComm-Oncology | Development of covalent inhibitors: Principle, design, and application in cancer

Number of publications found in the SciFinder® search for covalent inhibitors closely related to targeting different amino acid residues.Covalent inhibitors have been a rapidly growing field in drug d....

2023-10-31