MedComm-Biomaterials and Applications | Recent progress in orodispersible films-mediated therapeutic applications: A review

(A) Orodispersible films (ODFs) embedded with poorly water-soluble active pharmaceutical ingredients (APIs) formulated by various formulation strategies (image reprinted with permission from Ref.Orodi....

2023-05-31

MedComm-Biomaterials and Applications | Nanobiotechnology-mediated radioimmunotherapy treatment for triple-negative breast cancer

Mechanism of radiotherapy-induced abscopal effect combined with immunotherapy. CTLA-4, cytotoxic T-lymphocyte-associated antigen 4; PD-1, programmed death 1; PD-L1, programmed death-ligand 1; TNBC, tr....

2023-04-30

MedComm-Biomaterials and Applications | Dendrimer and dendrimer gel-derived drug delivery systems: Breaking bottlenecks of topical administration of glaucoma medications

Two major barriers to topical ocular drug delivery. Reprinted with permission from Li et al.Due to high structural flexibility, multidrug carrying capability, and tunable size, dendrimers have been us....

2023-03-31

MedComm-Biomaterials and Applications | 2-Hydroxy-1,4-naphthoquinone [Lawsone] integrated rare-earth hybrid materials as biocompatible UV/IR filter agents

Crystal phase and chemical interphase characterization of rare-earth systems and their hybrids: (A, B) XRD patterns of as-dried rare-earths and rare-earth hybrid systems, respectively; (C) FTIR spectr....

2023-02-28

MedComm-Biomaterials and Applications | Applications of scanning ion conductance microscope in biomedical fields

Imaging modes of scanning ion conductance microscopy (SICM). (A) In direct current (DC) mode, once the probe is close to the sample, the ion electricity decays rapidly. This key feature provides a fee....

2023-01-31

MedComm-oncology | Delivering CAR-T cells into solid tumors via hydrogels

Schematic illustration of the regional codelivery of CAR-T cells and therapeutic agents via hydrogels for the treatment of solid tumors. CAR, chimeric antigen receptor.Chimeric antigen receptor (CAR)-....

2023-07-31

MedComm-oncology | NKT cells contribute to alleviating lung metastasis in adenoid cystic carcinoma

UMAP image of three cases of primary and metastatic tumors. (A) Primary lesion, inflammatory phenotype without MYB-NFIB fusion. (B) Primary lesion, immune-exclusive phenotype with MYB-NFIBSalivary ade....

2023-06-30

MedComm-oncology | Precision gas therapy by ultrasound-triggered for anticancer therapeutics

Schematic overview of ultrasound-triggered gas therapy. Under ultrasound irradiation, the gas released molecules are released gases, for example, NO, O2, CO, CO2, for tumor therapy.In recent years, ul....

2023-05-31

MedComm-oncology | Fatty acids in cancer: Metabolic functions and potential treatment

Fatty acid (FA) metabolism in cancer cells. FAs can be de novo synthesized from citrate via ATP citrate lyase (ACLY), acetyl-CoA carboxylase (ACC), and FA synthase (FASN). Exogenous FAs can enter cell....

2023-04-30