Molecular Biomedicine | Multimodality molecular imaging of the alveolar-capillary barrier in lung disease using albumin based optical and PET tracers

Inflammatory changes caused by viruses, bacteria, exposure to toxins, commonly used drugs and even surgical intervention have the potential of causing abnormal epithelial permeability, which is manife....

2021-01-14

Mol Biomed

 
MedComm | Visualized analysis of trends and hotspots in global oral microbiome research: A bibliometric study

The oral microbiome contains numerous bacteria, which directly or indirectly participate in various human functions and continuously exchange signals and substances with the human body, significantly ....

2021-01-12

MedComm

 
MedComm | Incidence and risk factors of second primary cancer after the initial primary human papillomavirus related neoplasms

Human papillomavirus (HPV) infection is a common viral infection, with its relatively high prevalence (11% in oral cavity, 26.8% for females in genital organs, 14% for females in anus, 45.2% for males....

2020-12-31

MedComm

 
Molecular Biomedicine | Nose to brain delivery of antiretroviral drugs in the treatment of neuroAIDS

More than 35 years ago, HIV (Human Immunodeficiency Virus) was reported as a unique infection with apparent death. Nowadays, NeuroAIDS (Neuro Acquired Immunodeficiency Syndrome) or HIV (Human Immunode....

2020-12-29

Mol Biomed

 
Molecular Biomedicine | Update on treatment and preventive interventions against COVID-19: an overview of potential pharmacological agents and vaccines

The outbreak of coronavirus disease 2019 (COVID-19) triggered by the new member of the coronaviridae family, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has created an unprecedented ....

2020-12-18

Mol Biomed

 
MedComm | Development of pathological reconstructed high-resolution images using artificial intelligence based on whole slide image

Pathological analysis is an important approach to diagnose diseases, particularly malignant tumors. The whole slide image (WSI), which meets the desired characteristics of high-definition, high-speed,....

2020-12-17

MedComm

 
Molecular Biomedicine | Low dose of emetine as potential anti-SARS-CoV-2 virus therapy: preclinical in vitro inhibition and in vivo pharmacokinetic evidences

The global pandemic of Coronavirus disease 2019 (COVID-19) has attracted extensive drug searching interets for the new coronavirus SARS-CoV-2. Currently, several clinically used “old” drugs have been ....

2020-12-09

Mol Biomed

 
MedComm | Bone marrow mesenchymal stem cell-conditioned medium facilitates fluid resolution via miR-214-activating epithelial sodium channels

Acute lung injury (ALI) is featured with severe lung edema at the early exudative phase, resulting from the imbalance of alveolar fluid turnover and clearance. Mesenchymal stem cells (MSCs) belong to ....

2020-12-07

MedComm

 
MedComm | The biological role of metabolic reprogramming in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, characterized by early metastasis and resistance to all forms of treatment. The extremely high mortality rate of patients wit....

2020-11-27

MedComm