Molecular Biomedicine | Developing inhaled protein therapeutics for lung diseases

Biological drugs are revolutionising the treatment and management of many serious illnesses including cancer, autoimmune disorders, and rare genetic diseases, with about a third of all new drug approv....


Mol Biomed

Molecular Biomedicine | The bone marrow niche components are adversely affected in sepsis

In this study, Prof. Botao Ning et al provdied a investigation of the dynamic change of BM niche components in sepsis process for the first time.


Mol Biomed

MedComm | Zeolite in tissue engineering: Opportunities and challenges

As a microporous tectosilicate, zeolite has been well known for its potentiality in tissue engineering applications, especially when it comes to provide a biological microenvironment. However, researc....



MedComm | Effective antitumor activity of 5T4‐specific CAR‐T cells against ovarian cancer cells in vitro and xenotransplanted tumors in vivo

Ovarian cancer is considered to be the most lethal gynecologic malignancy, and despite the development of conventional therapies and new therapeutic approaches, the patient's survival time remains sho....



Molecular Biomedicine | Profiling chromatin regulatory landscape: insights into the development of ChIP-seq and ATAC-seq

Prof. Yongyou Zhang provided a detailed discussion of the development of ChIP-seq & ATAC-seq and their current applications in scientific research.


Mol Biomed

STTT | NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential

Nicotinamide adenine dinucleotide (NAD+) and its metabolites function as critical regulators to maintain physiologic processes, enabling the plastic cells to adapt to environmental changes including n....



Molecular Biomedicine | cGAS/STING: novel perspectives of the classic pathway

Researchers summerized the role cGAS/STING pathway plays in various pathological and physiological process and emphasized its involvment in some “nontraditional” way.


Mol Biomed

Molecular Biomedicine | Development of a novel TLR8 agonist for cancer immunotherapy

Toll-like receptors (TLRs) play a vital role in both innate and adaptive immune responses, which means they are also indispensable in tumorigenesis. Up to now, some TLRs, such as TLR8, TLR4, TLR7 and ....


Mol Biomed

Molecular Biomedicine | Revisiting cancer hallmarks: insights from the interplay between oxidative stress and non-coding RNAs

Cancer is one of the most common disease worldwide, with complex changes and certain traits which have been described as “The Hallmarks of Cancer.” Despite increasing studies on in-depth investigation....


Mol Biomed