MedComm Introduction

MedComm is a peer-reviewed, online open access (OA) journal. The journal publishes a wide variety of works that provide novel insights into all aspects of medicine on the basis of novelty, timeliness



Molecular Biomedicine Introduction

Molecular Biomedicine is a peer-reviewed, online open access (OA), multidisciplinary journal that publishes the pioneer works of biomedicine, emphasizing on pathogenic mechanism and innovative


Mol Biomed

Signal Transduction and Targeted Therapy Introduction

Signal Transduction and Targeted Therapy is an open access journal, which aims to accomplish timely publication of the latest discoveries and progress in both basic science and clinical research



MedComm | Molecular mechanisms of chemo- and radiotherapy resistance and the potential implications for cancer treatment

Cancer is a leading cause of death worldwide. Surgery is the primary treatment approach for cancer, but the survival rate is very low due to the rapid progression of the disease and presence of local ....



MedComm | Demethylzeylasteral inhibits proliferation, migration, and invasion through FBXW7/c-Myc axis in gastric cancer

Gastric cancer (GC) is one of the most familiar malignancy in the digestive system. Demethylzeylasteral (Dem), a natural functional monomer extracted from Tripterygium wilfordii Hook F, shows anti-tum....



MedComm | Insights on the structure–function relationship of human multidrug resistance protein 7 (MRP7/ABCC10) from molecular dynamics simulations and docking studies

ATP-binding cassette (ABC) transporters superfamily mediates multidrug resistance in cancer by extruding structurally distinct chemotherapeutic agents, causing failure in chemotherapy. Among the 49 AB....



Molecular Biomedicine | Targeting regulatory T cells for immunotherapy in melanoma

Regulatory T cells (Tregs) are essential in the maintenance of immunity, and they are also a key to immune suppressive microenvironment in solid tumors. Many studies have revealed the biology of Tregs....


MedComm | Neoantigen-reactive T cell: An emerging role in adoptive cellular immunotherapy

Adoptive cellular immunotherapy harnessing the intrinsic immune system for precise treatment has exhibited preliminary success against malignant tumors. As one of the emerging roles in adoptive cellul....



Molecular Biomedicine | GMPPB-congenital disorders of glycosylation associate with decreased enzymatic activity of GMPPB

The congenital disorders of glycosylation (CDG) are a family of metabolic diseases in which glycosylation of proteins or lipids is deficient. GDP-mannose pyrophosphorylase B (GMPPB) mutations lead to ....


Mol Biomed